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Principles of Process Research and Chemical Development in the Pharmaceutical Industry

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This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.

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Principles of Process Research and Chemical Development in the Pharmaceutical Industry, Oljan Repic

Language
Released
1998
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(Hardcover)
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Title
Principles of Process Research and Chemical Development in the Pharmaceutical Industry
Language
English
Released
1998
Format
Hardcover
Pages
273
ISBN10
0471165166
ISBN13
9780471165163
Series
Description
This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.