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Pharmaceutical Powder Compaction Technology

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Compaction of powder constituents--both active ingredient and excipients--is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of <b>Pharmaceutical Powder Compaction Technology</b> guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients

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Pharmaceutical Powder Compaction Technology, Metin Celik

Language
Released
2011
Binding
(Hardcover)
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Title
Pharmaceutical Powder Compaction Technology
Language
English
Publisher
CRC Press
Released
2011
Format
Hardcover
Pages
344
ISBN10
142008917X
ISBN13
9781420089172
Series
Description
Compaction of powder constituents--both active ingredient and excipients--is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of <b>Pharmaceutical Powder Compaction Technology</b> guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. This unique reference covers: The physical structure of pharmaceutical compacts Bonding phenomena that occur during powder compaction Compression mechanisms of pharmaceutical particles Theories and basic principles of powder compaction New topics include: Compaction data analysis techniques The migration of powder constituents into commercial manufacture Instrumentation for compaction Compaction functionality testing, which is likely to become a USP requirement Design space for compaction Metrics required for scalability in tablet compression Interactive compaction and preformulation database for commonly used excipients