In Membrane Transporters in Drug Discovery and Development: Methods and Protocols, expert researchers provide practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development.
This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treatment systems using chronotherapy and chronobiology-based biomarkers as a general system of medicine. Succinct yet comprehensive, Cellular Rhythms and Networks, part of SpringerBriefs in Cell Biology presents a novel framework for clinical applications in personalized and systems medicine. It is invaluable reading for researchers and clinicians in cell biology, mood disorders, and systems medicine.
This book offers a comprehensive overview of the latest discoveries and systems approaches in the multi-disciplinary field of psychoneuroimmunology (PNI), which underpins the scientific basis for mind-body relationships and the advancement of personalized medicine. It emphasizes systems biology studies related to complex mechanisms like stress and inflammation, highlighting the strong connections between stress, inflammation, and various disorders such as obesity, cardiovascular disease, diabetes, skin conditions, and sleep disorders. As inflammation serves as a critical link among these diseases, understanding this relationship may reveal systemic therapeutic targets. The book also addresses translational medicine, focusing on the application of PNI in clinical settings. A significant challenge in bioscience is translating basic scientific discoveries into improved clinical outcomes. By exploring the translational implications of PNI, the text discusses integrative interventions that can modulate stress responses and encourage healthier behaviors. Notably, it provides a broad overview of PNI-related integrative interventions, including nutritional supplements, meditation, and other mind-body strategies. Covering everything from basic concepts to clinical applications, the book enhances the understanding and development of PNI toward establishing personalized and mind-body medicine.