Focusing on hot-melt extrusion (HME), this book explores its significant role in manufacturing and pharmaceutical research over the past thirty years. It highlights HME's effectiveness in creating solid dispersions for controlled and targeted drug delivery, enhancing bioavailability, and masking the taste of bitter APIs. The text covers various aspects, including equipment, processing technologies, and novel formulation designs, while presenting multiple case studies that demonstrate HME's applications in improving oral drug delivery systems.
This professional guide provides an authoritative overview of 3D and 4D printing technology in the biomedical and pharmaceutical fields. Featuring contributions from a diverse panel of academic scholars and industry experts, it presents the latest research and innovations in these applications. The book delves into process optimization, engineering, and platform technology essential for printed medicine. Key topics include shape memory polymers, 4D bio-fabrications, and bone printing, highlighting the potential of 3D printing for pharmaceutical drug delivery. It examines new fabrication processes, bio-scaffolding, and current trends and challenges in biofabrication for 3D and 4D bioprinting. This vital resource offers a comprehensive guide to the technology, including details on the first FDA-approved 3D printing platform for a pharmaceutical product and a review of existing 3D printed pharmaceutical products. It also presents recent advances in novel materials for biomedical applications. Aimed at pharmaceutical chemists, medicinal chemists, biotechnologists, and pharma engineers, this book explores the key aspects of medical and pharmaceutical product printing, along with the challenges and advancements in their development.
