The book presents a novel theory on the nature of time, challenging the prevailing belief that time and space are fundamentally similar. Ulrich Meyer offers a thorough defense of a 'modal' perspective, highlighting the parallels between times and possible worlds as understood in modal logic. This approach is positioned as compatible with the theory of relativity, providing a fresh viewpoint in the ongoing discourse on the nature of time.
This book provides a comprehensive overview of the advancements in tissue engineering and regenerative medicine, highlighting the significant growth in the field over the past decade. With progress in genetic medicine and stem cell technology, the potential to influence cell and tissue performance has expanded, leading to a broader scope in regenerative medicine. Various approaches are now routinely used in clinical practice, while many others are in clinical studies or preclinical testing. Given these developments, there is a pressing need for detailed information for researchers and clinicians navigating this rapidly evolving field. The content is organized didactically, covering general aspects such as social, economic, and ethical considerations, along with fundamental biological aspects like stem cell medicine and genetic engineering. It also addresses classic tissue engineering methods, biotechnological issues like scaffolds and bioreactors, and includes a review of clinical applications across various medical specialties. Written by leading experts in their fields, the 68 chapters encapsulate the latest intellect and experience in this dynamic biomedical area, making it an essential resource for understanding the essentials of tissue engineering and regenerative medicine.
Bone and Cartilage Engineering provides a complete overview of recent knowledge in bone and cartilage tissue engineering. It follows a logical approach to the various aspects of extracorporal bone and cartilage tissue engineering. The cooperation between a basic scientist and a clinician made it possible to structure the book's content and style according to the interdisciplinary character of the field. The comprehensive nature of the book, including detailed descriptions of laboratory procedures, preclinical approaches, clinical applications, and regulatory issues, will make it an invaluable basis for everyone working in this field. This book will serve as a fundamental tool for basic researchers to establish or refine tissue engineering techniques as well as for clinicians to understand and use this modern therapeutic option.
Algorithms that have to process large data sets have to take into account that the cost of memory access depends on where the data is stored. Traditional algorithm design is based on the von Neumann model where accesses to memory have uniform cost. Actual machines increasingly deviate from this model: while waiting for memory access, nowadays, microprocessors can in principle execute 1000 additions of registers; for hard disk access this factor can reach six orders of magnitude. The 16 coherent chapters in this monograph-like tutorial book introduce and survey algorithmic techniques used to achieve high performance on memory hierarchies; emphasis is placed on methods interesting from a theoretical as well as important from a practical point of view.