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Thomas M. Jessell

    This author's primary focus is on the intricate mechanisms of the nervous system and the biological underpinnings of movement. Their research delves into how nerve cells communicate and how these signals translate into coordinated physical actions. They are dedicated to unraveling the complex molecular processes that govern neural function and motor control. This work aims to deepen our understanding of brain plasticity and the potential for therapeutic interventions.

    Molecular and Cellular Approaches to Neural Development
    Principles of Neural Science
    • Principles of Neural Science

      4th Edition

      • 1414 pages
      • 50 hours of reading

      Now in resplendent color, the new edition continues to define the latest in the scientific understanding of the brain, the nervous system, and human behavior. Each chapter is thoroughly revised and includes the impact of molecular biology in the mechanisms underlying developmental processes and in the pathogenesis of disease. Important features to this edition include a new chapter - Genes and Behavior; a complete updating of development of the nervous system; the genetic basis of neurological and psychiatric disease; cognitive neuroscience of perception, planning, action, motivation and memory; ion channel mechanisms; and much more.

      Principles of Neural Science
      4.5
    • This comprehensive and authoritative volume explores recent advances in understanding early neural development at molecular and cellular levels. The authors detail applications of molecular genetic methods in studying neural induction, neuronal phenotypes, and specific connection patterns. They analyze new information from modern techniques for identifying, cloning, deleting, and introducing specific genes, as well as for labeling neuronal or glial precursors and imaging individual neurons or parts of neurons. Chapters highlight the use of various model organisms, including fruit flies, nematode worms, zebrafish, Xenopus frogs, chicks, and mice. The improved conservation of DNA and protein sequences, along with accessible gene and protein databases, allows for rapid identification of gene homologues across species separated by significant evolutionary distances. Several chapters feature collaborations between researchers specializing in vertebrates and invertebrates, illustrating that despite differences in nervous system structure, many molecular players and cellular processes are conserved. This volume is of great practical interest to researchers, graduate students, and post-doctoral fellows in developmental, cell and molecular biology, genetics, and neuroscience.

      Molecular and Cellular Approaches to Neural Development