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Iwan L. Bonta

    Inflammation, mechanisms and their impact on therapy
    Recent developments in the pharmacology of inflammatory mediators
    Connective tissues changes in rheumatoid arthritis and the use of penicillamine
    • InhaltsverzeichnisOpening remarks.Involvement of mediators in the interaction of platelets and carrageenan.Platelets and mediators in the carrageenin rat paw oedema.Comparison of the mediator release from platelets and the development of acute inflammation in rats which lack prostaglandin precursors.Glucocorticoid effect on the prostaglandin system in adipose tissue.Effect of glucocorticosteroids on the release of prostaglandin-like substances in anaphylaxis.Effects of anti-inflammatory drugs on the carrageenin-induced hind paw inflammation of rats deprived of endogenous precursors of prostaglandins.Metyrapone: A possible tool in investigating the role of endogenous corticosteroids in inflammation.Prostaglandins and complement changes in some conditions related to inflammation.Involvement of complement and kinins in some non-immunogenie paw inflammations in rats.Inflammatory responses of the rabbit eye to prostaglandins.Some biochemical complexities of inflammatory disease affecting drug action.Inflammation inhibiting properties of rat alpha-foetoprotein (rat-alpha2-macroglobulin), an acute phase reactant.Biodistribution of salicylates: A clue to the understanding of some effects and side-effects.

      Recent developments in the pharmacology of inflammatory mediators
    • This book comprises the proceedings of an view of the subject to an audience of clinicians. Advanced Teaching Course held in Rotterdam, The outcome is the present book. Due to the ex The Netherlands, on November 25-26, 1976. pert knowledge and didactic capacity of the con The history of this Course goes back to tributors, we hope the book will be of some use in 1972, when a small, loosely connected group of making research views accessible to those Dutch researchers, who were fascinated by in engaged in clinical practice. vestigating fundamental problems of inflam In organizing this Course we enjoyed the mation, felt the necessity of coming together support of the 'Gerrit Jan Mulder Foundation', from time to time to exchange ideas about their which aims to promote post-doctoral training in work. The desire for such informal gatherings led the Medical Faculty of the Erasmus University to the foundation of the Inflammation Section of Rotterdam. We are particularly obliged to Dr M.

      Inflammation, mechanisms and their impact on therapy