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Annette Simon

    Annette Simon is an author and illustrator for young readers. Her artistic talent, evident from a young age, blossomed into an award-winning career in advertising. Now, she channels this creative energy into captivating stories and illustrations for children. Simon finds deep fulfillment in this work, considering it an honor to connect with young imaginations and foster their understanding of the world.

    "Bleiben will ich, wo ich nie gewesen bin"
    The influence of hydrodynamics on the dissolution of poorly soluble drugs
    Spine Poems
    Robot Zombie Frankenstein!
    Robot Burp Head, Smartypants!
    Mocking Birdies
    • 2022

      "A charming, clever, and original collection of more than 100 spine poems-a popular form of found poetry composed by arranging book spines"-- Provided by publisher

      Spine Poems
    • 2014

      Robot Burp Head, Smartypants!

      • 40 pages
      • 2 hours of reading

      The story features rival robots engaging in a humorous competition filled with quirky antics and playful challenges. As they navigate their zany rivalry, expect a mix of laughter and surprises, showcasing their unique personalities and inventive antics. The narrative promises a lighthearted exploration of friendship and rivalry in a whimsical setting.

      Robot Burp Head, Smartypants!
    • 2012

      This lively cumulative tale combines robots, various shapes, and a whimsical theme centered around pie, making it ideal for energetic story times. The engaging narrative promises a fun and interactive experience for young readers, encouraging participation and imagination through its playful mash-up of elements.

      Robot Zombie Frankenstein!
    • 2005

      Mocking Birdies

      • 32 pages
      • 2 hours of reading

      The story features two playful bird characters, the Blue Bird and the Red Bird, who engage in a delightful battle of mimicking each other. Through their interactions, the book promotes themes of turn-taking and harmony, inviting young readers to explore the joy of imitation while learning the importance of cooperation. The vibrant illustrations complement the narrative, making it an engaging experience for children.

      Mocking Birdies
    • 2002

      Dissolution testing is an important tool in forecasting the in vivo performance of drugs and their formulations. In recent years many efforts have been made to modify the in vitro conditions so that they better simulate in vivo behaviour. However, Iittle is known about in vivo hydrodynamics and how weil the in vitro testing conditions correspond to them. Aprerequisite to modelling in vivo hydrodynamics with a dissolution test system is to characterize the in vivo hydrodynamics in such a way that the results can be adapted to the in vitro setting. A fistulated dog model was therefore established to selectively study the influence of the particle size and GI hydrodynamic conditions on the in vivo dissolution. On the basis of its poor solubility (aqueous solubility: 1 mg/I at 37°C), high lipophilicity (log P 4.5), suitable pharmacokinetics and the availability of a variety of particle sizes, the neutral and stable antihypertensive drug felodipine was chosen as a model substance for investigating hydrodynamic effects on dissolution in both the canine model and in vitro.

      The influence of hydrodynamics on the dissolution of poorly soluble drugs