Dieter Häussinger Book order

In 2013, the Hirsch Institute of Tropical Medicine (HITM) was inaugurated as part of the Department of Gastroenterology, Hepatology, and Infectious Diseases at Heinrich Heine University Düsseldorf, led by Professor Dieter Häussinger. The HITM focuses on scientific knowledge transfer, postgraduate medical training, and research in tropical medicine and infectious diseases. This publication details the institute's history, activities, and future perspectives, offering insights into its construction in Africa and the experiences of its staff. Professor Häussinger, who also directs the Department of Gastroenterology, Hepatology, and Infectious Diseases, emphasizes clinical and experimental hepatology and gastroenterology while advancing the field of infectious diseases. He has played a pivotal role in certifying his department as a Center of Infectious Diseases, establishing a tropical medicine and infectious diseases outpatient clinic, and creating the Liver and Infectious Diseases Center, which is the only treatment facility in North Rhine-Westphalia for highly infectious patients. The HITM represents a significant step forward in addressing tropical medicine and infectious disease challenges.

This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in gastroenterology. Special topic issues are included in the subscription.

This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in gastroenterology. Special topic issues are included in the subscription.

One major function of the liver is the uptake of endo- and xenobiotics from the bloodstream and their excretion into bile. The transport systems involved in hepatobiliary transport have been recently cloned and characterized at the molecular level and it is becoming clear that mutations and polymorphisms of individual transporter molecules underlie a variety of liver diseases. Furthermore, new research has shown that bile acids, whose function in digestion is long known, also behave as signal molecules in a variety of organs, including the intestinal and biliary epithelia, sinusoidal endothelial and immune cells. This book provides indepth surveys on the structure and function of transport molecules involved in hepatobiliary transport, on the role of different bile acids receptors in various organs and their function in health and disease, the mechanisms of bile salt-induced apoptosis and hepatocyte protection, and the role of transporter mutations as causes and modifiers of liver diseases. The book will be of interest not only for biochemists, structural chemists and biologists, but also for clinicians.

This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Special topic issues are included in the subscription.

understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.