Thomas Dittmar Book order

1) Introduction; T. Dittmar, K.S. Zänker Bone marrow-derived stem cells 2) Hematopoietic stem and progenitor cells in clinical use - transplantation and mobilization; M. Punzel 3) Ex-vivo Expansion of HSPCs; Y. Wei 4) Modulation of hematopoietic stem/progenitor migration; T. Dittmar5) Properties of mesenchymal stem cells to consider for cancer cell therapy; J. Stagg Embryonic stem cells 6) Alternative embryonic stem cell sources; T. Saric, J. Hescheler 7) Cell therapy in Parkinson's Disease; R. Laguna Goya, R. A. Barker 8) Transplantation of stem cells and their derivatives in the treatment of multiple sclerosis; E. Larsen, I. Duncan Cancer Stem Cells 9) Cancer - A Stem Cell-based disease?; J. E. Trosko 10) Stem Cell Niche vs. Cancer Stem Cell Niche - Differences and Similarities; B. C. Baguley, G. J. Finlay 11) The chronically inflamed microenvironment and cancer stem cells; H. Li, C. Stoicov, X. Fan, J. Cerny, J.M. Houghton 12) Does the chronically inflamed periodontium harbour cancer stem cells?; W.-D. Grimm, W. H. Arnold, S. Becher, A. Dannan, G. Gassmann, S. Philippou, T. Dittmar, G. Varga 13) Cancer Stem Cells in the Haematopoietic System/ Haematopoietic Stem/ Progenitor Cell Disorders; M. Müschen 14) Cancer stem cells in solid tumors; M. G. Nafus, A. Y.Nikitin 15) 'One for all' or 'All for one'? - The necessity of cancer stem cell diversity in metastasis formation and cancer relapse; T. Dittmar, C. Nagler, S. Schwitalla, K. Krause, J. Seidel, G. Reith, B. Niggemann, K. S. Zänker 16) Elimination of Cancer Stem Cells; A. Sagrera, J. Pérez-Losada, M. Pérez-Caro, R. Jiménez, I. Sánchez-García, C. Cobaleda 17) Potential molecular therapeutic targets in cancer stem/progenitor cells: Are ATP-binding cassette membrane transporters appropriate targets to eliminate cancer-initiating cells?; M. Mimeault, S. K. Batra

The last two decades have highlighted the crucial role of the local microenvironment in cancer progression. Cancer arises not merely from mutations in individual cells but from a complex interplay involving tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines, and DNA-damaging agents. This book offers a comprehensive overview of how infections and chronic inflammatory conditions can lead to malignant phenotypes, a concept first proposed by Rudolf Virchow in 1863. Experts in the field discuss novel insights, including the involvement of stem cells and aneuploidy in carcinogenesis. It details specific pathogens linked to certain cancers, such as Helicobacter pylori with gastric neoplasia and schistosomiasis with bladder cancer. The mechanisms of carcinogenesis and the types of cells that can transform into malignant forms are thoroughly examined, with a focus on stem cells recently identified as contributors to cancer. Additional chapters explore the role of chemokines in metastasis and methods for visualizing metastasis in 3D models and living organisms. The growing understanding of the inflammatory microenvironment's impact on carcinogenesis will inform new anti-inflammatory strategies to combat tumor development. This book is vital for scientists and clinicians engaged in cancer research and prevention.