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Zeʾēv Hôḵberg

    Vitamin D and rickets
    Endocrine control of skeletal maturation
    Practical algorithms in pediatric endocrinology
    • 2017

      Algorithms provide a logical, concise and cost-effective approach to medical reasoning: utilizing a concise, step-by-step approach based upon clues from the history, physical examination and laboratory studies, algorithms help avoid excessive unnecessary procedures and testing. The 3rd, revised edition of Practical Algorithms in Pediatric Endocrinology deals with practical issues of child growth, puberty, diseases of the endocrine glands, sexual differentiation, as well as aberrations of water, electrolyte, mineral and carbohydrate metabolism. Fifty-six clinical issues are covered by an algorithmic approach, breaking down long lists and tables of differential diagnosis into smaller, more manageable ones. Common clinical symptoms, signs and laboratory abnormalities are classified as they present themselves at the patient’s bedside. This book is aimed at general practitioners and pediatricians, in particular those who are not exposed to pediatric endocrine problems on a daily basis, and at trainees in endocrinology and pediatric endocrinology as they acquire familiarity with clinical problem solving to make rational choices when facing clinical dilemmas.

      Practical algorithms in pediatric endocrinology
    • 2002

      Endocrine control of skeletal maturation

      • 111 pages
      • 4 hours of reading

      As a common concept 'bone age' is felt to be an expression of the biological maturity of a child. Inferring from bone maturity, the clinician can contemplate diagnostic considerations and evaluate height prediction. A radiogram of the hand and wrist may provide additional information that is not being evaluated by reading of a 'bone age'. Although it reveals only calcified elements it provides a glimpse into a whole variety of processes in bone and cartilage growth, differentiation and calcification which, in turn, are regulated by control mechanisms. Thyroid hormones, sex steroids, calcium regulating hormones are but a few of these control mechanisms, and their effect may become evident when radiograms are carefully examined. This book illustrates how to interpret the biological mechanisms of growth from hand and wrist x-rays reviewing at the same time the anatomical and histological maturation of long bones and cuboid bones. It summarizes the endocrine regulation.

      Endocrine control of skeletal maturation