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Methylotrophic yeasts have attracted increasing interest as useful systems for fundamental research and applied purposes. Hansenula polymorpha in particular has become a preferred organism for the production of recombinant proteins on an industrial scale. Product examples range from therapeutics such as hepatitis B vaccines to industrial enzymes like the feed additive phytase. This book is addressed to researchers and scientists working in the field and provides a comprehensive, up-to-date overview of the present status of Hansenula polymorpha research, applications and methods. Aspects of the organism ranging from systematics, genetics, methanol metabolism and peroxisomal function to its use as a technology platform for the production of recombinant proteins are covered. A detailed chapter on laboratory methods is also included.
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Hansenula polymorpha, Gerd Gellissen
- Language
- Released
- 2002
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- Title
- Hansenula polymorpha
- Language
- English
- Authors
- Gerd Gellissen
- Publisher
- Wiley-VCH
- Publisher
- 2002
- ISBN10
- 3527303413
- ISBN13
- 9783527303410
- Category
- University and college textbooks
- Description
- Methylotrophic yeasts have attracted increasing interest as useful systems for fundamental research and applied purposes. Hansenula polymorpha in particular has become a preferred organism for the production of recombinant proteins on an industrial scale. Product examples range from therapeutics such as hepatitis B vaccines to industrial enzymes like the feed additive phytase. This book is addressed to researchers and scientists working in the field and provides a comprehensive, up-to-date overview of the present status of Hansenula polymorpha research, applications and methods. Aspects of the organism ranging from systematics, genetics, methanol metabolism and peroxisomal function to its use as a technology platform for the production of recombinant proteins are covered. A detailed chapter on laboratory methods is also included.