Growth Factors and Cytokines in Skeletal Muscle Development, Growth, Regeneration and Disease

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This book explores the critical roles of growth factors and cytokines in skeletal muscle biology. The extracellular environment significantly influences skeletal muscle, with a diverse array of soluble factors that regulate responses to various stimuli, including exercise, trauma, and neuromuscular diseases. The chapters detail growth factors that directly impact muscle cells and those affecting non-muscle cells that contribute to overall muscle function. Advances in systems biology enable the mapping of signaling networks regulated by multiple growth factors, contrasting with earlier studies that focused on isolated factors in tissue culture. The content ranges from in-depth analyses of individual growth factors to the intricate interactions among multiple soluble factors that govern both functional and dysfunctional muscle states. This volume is tailored for readers across various research fields, including muscle biology, physiology, and those studying conditions affecting skeletal muscle directly or indirectly.