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This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e. g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.
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Translational Neuropsychopharmacology, Trevor W. Robbins
- Language
- Released
- 2018
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- Title
- Translational Neuropsychopharmacology
- Language
- English
- Authors
- Trevor W. Robbins
- Publisher
- Springer
- Publisher
- 2018
- ISBN10
- 3319816306
- ISBN13
- 9783319816302
- Category
- Health / Medicine
- Description
- This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e. g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.