Grapefruit - Boon or Curse?

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Grapefruit and grapefruit juice can dangerously interact with numerous medications. The flavonoids in grapefruit inhibit the CYP3A4 enzyme in both the small intestine and liver, leading to slowed metabolism and excretion of at least 85 drugs. This results in elevated blood levels of these medications, which can be toxic and cause severe side effects. Unfortunately, many patient information leaflets lack adequate warnings, and there are no cautionary labels on grapefruit juice or beer bottles. It's crucial for the pharmaceutical and food industries to address this issue. While grapefruit is healthy for those not on medication, it poses risks for individuals taking drugs for conditions such as heart issues, high blood pressure, blood thinners, cholesterol management, benzodiazepines, antidepressants, bladder relaxation, prostate problems, estrogen-containing contraceptives, and Viagra, among others. These health concerns can affect people of all ages. Always consult your doctor about potential grapefruit interactions when prescribed medication, and read patient information leaflets before taking any drugs. If you’re unable to read, ask family or friends for assistance. This book provides further insights into this important issue.