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Viral Interference of GB Virus C and Human Immunodeficiency Viruses
Different GB Virus C Proteins interfere with the Replication of HIV-1
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Co-infection of HIV with GB Virus C (GBV-C) presents a paradox where long-term GBV-C viremia correlates with improved survival rates in HIV patients, despite the lack of definitive causal evidence. Research indicates that GBV-C may inhibit various HIV strains through complex mechanisms, including specific proteins that block HIV entry and replication. Additionally, GBV-C induces antibodies that neutralize HIV, suggesting potential avenues for new drug and vaccine development. This interplay between GBV-C and HIV highlights important clinical implications for treatment strategies.
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Viral Interference of GB Virus C and Human Immunodeficiency Viruses, Susan Jung
- Language
- Released
- 2015
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- Title
- Viral Interference of GB Virus C and Human Immunodeficiency Viruses
- Subtitle
- Different GB Virus C Proteins interfere with the Replication of HIV-1
- Language
- English
- Authors
- Susan Jung
- Publisher
- Südwestdeutscher Verlag für Hochschulschriften AG Co. KG
- Released
- 2015
- Format
- Paperback
- Pages
- 124
- ISBN13
- 9783838123837
- Category
- Health / Medicine
- Description
- Co-infection of HIV with GB Virus C (GBV-C) presents a paradox where long-term GBV-C viremia correlates with improved survival rates in HIV patients, despite the lack of definitive causal evidence. Research indicates that GBV-C may inhibit various HIV strains through complex mechanisms, including specific proteins that block HIV entry and replication. Additionally, GBV-C induces antibodies that neutralize HIV, suggesting potential avenues for new drug and vaccine development. This interplay between GBV-C and HIV highlights important clinical implications for treatment strategies.