Paving the Way for Better Care: A Pilot Study on the Genetics of Congenital Heart Disease in South Africa

Congenital heart disease (CHD) involves various structural heart abnormalities present at birth, making it the most prevalent birth defect globally, affecting about 1 in 100 newborns. The spectrum of CHD ranges from mild issues to severe conditions that may require multiple surgeries. Despite advancements in care, it remains a significant cause of infant mortality, particularly in low- and middle-income countries, where nearly one million childhood deaths are attributed to CHD each year, highlighting the urgent need for improved medical management and resources.