Jens Nielsen Book order

This work offers a comprehensive overview of systems biology, detailing experimental and computational approaches for studying biological systems. Each chapter serves as an introduction to a specific branch of the field, presenting the current state of research and future directions. It explores integrative analysis methods for omics data and techniques for quantifying carbon fluxes in large metabolic networks, utilizing 13C labelled substrates and genome-scale metabolic models, with examples from Escherichia coli and human metabolism. The authors also discuss the application of these techniques to human health and cell factory engineering, emphasizing advancements in genome-scale models and regulatory networks. They underscore the relevance of this information to various biological processes, such as cellular aging, the immune system, and organogenesis. The book concludes with a discussion on recent genome editing advances, enabling precise genetic modifications and dynamic gene expression control. Part of the Advances in Biotechnology series, it encompasses all critical aspects of the field, with each volume crafted by leading experts.

Focusing on the principles and practices of bioreactions and bioreactors, this book integrates recent research with nearly 100 design examples and problems. It offers practical applications suitable for hands-on demonstrations and further research. Aimed at students in bioengineering, biotechnology, and various engineering disciplines, it serves as a comprehensive guide to understanding the complex interactions in bioprocessing.

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e. g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms. This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Covers trends in modern biotechnology All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated More information as well as the electronic version available at springeronline. com

Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology , developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.