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IARC Scientific Publications - 83: Long-term and Short-term Assays for Carcinogens

A Critical Appraisal

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  • 580 pages
  • 21 hours of reading

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This volume contains the papers presented at a meeting held in December 1985 to review the conduct and use of long- and short- term assays for the detection of chemical carcinogens. The meeting was attended by about 60 experts in the fields of carcinogenesis, mutagenesis, and cell biology.The series of reports on long-term carcinogenicity assays pay particular attention to three the role of pharmacokinetic data, early preneoplastic lesions in carcinogenesis, and the possibility for discerning the relative contribution of carcinogens to various stages of carcinogenesis. Thereports on short-term assays summarize, among other points, the principle and scientific basis of each assay and its relevance to carcinogen detection and to the multistage process of carcinogenesis.

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IARC Scientific Publications - 83: Long-term and Short-term Assays for Carcinogens, R. Montesano, H. Bartsch, H. Vainio, J. Wilbourn, H. Yamasaki, R.A. Griesemer, S. Venitt, International Program on Chemical Safety

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Released
1986
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Title
IARC Scientific Publications - 83: Long-term and Short-term Assays for Carcinogens
Subtitle
A Critical Appraisal
Language
English
Released
1986
Format
Paperback
Pages
580
ISBN10
9283211839
ISBN13
9789283211839
Series
Description
This volume contains the papers presented at a meeting held in December 1985 to review the conduct and use of long- and short- term assays for the detection of chemical carcinogens. The meeting was attended by about 60 experts in the fields of carcinogenesis, mutagenesis, and cell biology.The series of reports on long-term carcinogenicity assays pay particular attention to three the role of pharmacokinetic data, early preneoplastic lesions in carcinogenesis, and the possibility for discerning the relative contribution of carcinogens to various stages of carcinogenesis. Thereports on short-term assays summarize, among other points, the principle and scientific basis of each assay and its relevance to carcinogen detection and to the multistage process of carcinogenesis.