The narrative explores Harriet Tubman's courageous role in the Underground Railroad, highlighting her efforts to lead over 700 slaves to freedom. It emphasizes her impact on the Union Army during the Civil War, showcasing her bravery and dedication to the abolitionist cause. Through her actions, Tubman became a pivotal figure in the fight against slavery, illustrating the themes of resilience and heroism in the face of oppression.
The story chronicles the life of Agnes Gonxha Bojaxhiu, who transforms into the iconic Mother Teresa. It highlights her journey from Ireland to India, showcasing her dedication to charity and the impact of her work alongside the nuns who continued her mission. This leveled reader from National Geographic Kids provides an engaging exploration of her inspiring life and legacy.
Explore the remarkable lives and achievements of four pivotal figures in American history: George Washington Carver, known for his agricultural innovations; Rosa Parks, a key figure in the civil rights movement; Frederick Douglass, an influential abolitionist and orator; and Martin Luther King, Jr., a leader of nonviolent activism. This book highlights their contributions and the impact they had on society, offering insights into their struggles and triumphs in the pursuit of equality and justice.
The biography explores the life and accomplishments of Frederick Douglass, an influential abolitionist, writer, and orator. It highlights his significant achievements and the obstacles he overcame, making it an inspiring read for children. Designed for independent readers, the Level 2 text offers engaging and accessible information that encourages young readers to learn about Douglass's impactful legacy.
The enchanting life of Walt Disney, a beloved storyteller and entrepreneur, is explored in this biographic reader. Designed for fluent readers, the Level 3 text offers intriguing insights into Disney's journey, appealing to fans of Disneyland and Disney World. The book highlights his fascinating contributions to entertainment and storytelling, making it an engaging read for those interested in Disney's legacy.
Interstitial lung diseases (ILD) are a diverse group of chronic disorders affecting the distal lung, often unresponsive to current therapies and leading to lung parenchyma distortion and rapid respiratory failure. The disease's pathogenesis remains partially understood, with conditions like idiopathic pulmonary fibrosis (IPF) linked to initial alveolar epithelial cell injury, ER-stress, and apoptosis of type II alveolar epithelial cells (AECII). Collagen vascular diseases (CVD), which are immunologically mediated inflammatory disorders affecting connective tissue and vessels, frequently involve the lungs, particularly in Polymyositis (PM), Dermatomyositis (DM), and Systemic Sclerosis (SSc), where ILD significantly impacts morbidity and mortality. Autoantibodies, such as anti-histidyl-tRNA-Synthetase in PM/DM and various anti-Topoisomerase antibodies in SSc, are predictive of pulmonary involvement. This project hypothesized that these autoantibodies induce ILD development in CVD through AECII injury, leading to ER-stress and apoptosis. To investigate, HisRS, Topo1, Topo2α, and Topo2β were silenced in A549 cells, and topoisomerase inhibition was performed using topotecan and etoposide. Results indicated that silencing did not induce ER-stress or apoptosis, while topoisomerase inhibition did. Immunohistochemistry of lung sections from an SSc patient revealed ER-stress and apoptosis in AECIIs, suggesting that autoantibodies in CVD
The biography delves into the life of Supreme Court Justice Sonia Sotomayor, highlighting her journey to becoming the first Hispanic Supreme Court Justice. It addresses the challenges she encountered throughout her career, providing young readers with an inspiring story of resilience and achievement. Designed for independent readers, the level 3 text offers a comprehensive yet accessible exploration of her significant contributions to modern America.
Discover Pope Francis, born Jorge Mario Bergoglio in Buenos Aires, Argentina, and the first pope from the Americas. This children's Level 1 book is perfect for early independent readers or as a read-aloud experience, sharing the story of the pope who succeeded a living predecessor.
National Geographic Primary Readers is a high-interest series of beginning
reading books that have been developed in consultation with education experts.
The books pair magnificent National Geographic photographs with lively text by
skilled children's book authors across four reading levels.
