Lina Chouchene Books

Focusing on the reproductive effects of cadmium (Cd) and the protective role of zinc (Zn), this study investigates their interactions in female zebrafish (Danio rerio). It aims to elucidate the toxic impact of Cd and how Zn supplementation may mitigate these effects. The research examines various parameters, including ovarian function, tissue histology, and oxidative status, alongside the fixation of Cd and levels of Zn in tissues. Additionally, it explores the role of membrane transporters in these processes, providing insights into the underlying mechanisms of toxicity and protection.

The study investigates how cadmium (Cd), an endocrine disruptor, impacts estradiol signaling and female reproductive function, particularly in the presence of zinc (Zn). Utilizing both in vivo and in vitro experimental approaches, the research employs zebrafish and U251-MG astrocytic cells to analyze the effects of Cd and Zn on embryonic development and survival. Additionally, it examines the influence on estrogen receptor gene expression and brain aromatase levels, shedding light on the hormonal interactions critical for reproductive health.