Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

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Focusing on the critical aspect of sample size in clinical trials, the book offers a comprehensive guide to the principles and methods for calculating and recalculating sample sizes. It emphasizes the importance of determining an appropriate sample size to ensure the ethical, scientific, and economic integrity of clinical research. The content is designed to equip researchers with state-of-the-art techniques essential for planning successful trials, addressing the challenges posed by both insufficient and excessive sample sizes.