Late effect of sertraline on experimental depression in rats

The study explores the effects of neonatal sertraline treatment on body weight, depression, and exploratory behavior in young adult rats. The experimental group received a daily dose of 15 mg/kg of sertraline from the first to the twenty-first day of life, while the control group was administered distilled water. The research aims to understand how early intervention with a selective serotonin reuptake inhibitor influences behavioral outcomes later in life.