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The book delves into the genetic traits and structural changes of SARS-CoV-2 variants circulating globally, focusing on their evolution across different regions during the pandemic. It examines the implications of these mutations on the effectiveness of existing neutralizing antibody-based vaccines and treatments, supported by recent clinical data. Additionally, the author proposes strategies to mitigate immune escape in future COVID-19 therapies, providing a comprehensive understanding of the ongoing challenges posed by these viral variants.
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SARS-CoV-2 Spike Protein Convergent Evolution, Daniele Focosi
- Language
- Released
- 2021
- product-detail.submit-box.info.binding
- (Paperback)
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- Title
- SARS-CoV-2 Spike Protein Convergent Evolution
- Subtitle
- Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines
- Language
- English
- Authors
- Daniele Focosi
- Publisher
- Springer International Publishing
- Released
- 2021
- Format
- Paperback
- Pages
- 152
- ISBN13
- 9783030873233
- Series
- Description
- The book delves into the genetic traits and structural changes of SARS-CoV-2 variants circulating globally, focusing on their evolution across different regions during the pandemic. It examines the implications of these mutations on the effectiveness of existing neutralizing antibody-based vaccines and treatments, supported by recent clinical data. Additionally, the author proposes strategies to mitigate immune escape in future COVID-19 therapies, providing a comprehensive understanding of the ongoing challenges posed by these viral variants.